Fluticasone propionate generic

In rare cases, patients on inhaled fluticasone propionate may present with systemic eosinophilic conditions. Some of these patients have clinical features of vasculitis consistent with Churg-Strauss syndrome , a condition that is often treated with systemic corticosteroid therapy. These events usually, but not always, have been associated with the reduction and/or withdrawal of oral corticosteroid therapy following the introduction of fluticasone propionate. Cases of serious eosinophilic conditions have also been reported with other inhaled corticosteroids in this clinical setting. Physicians should be alert to eosinophilia , vasculitic rash, worsening pulmonary symptoms, cardiac complications, and/or neuropathy presenting in their patients. A causal relationship between fluticasone propionate and these underlying conditions has not been established.

Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen , estrogen , or mineralocorticoid receptors , thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (. mast cell , eosinophil , neutrophil , macrophages , and lymphocytes ) and mediators (. histamine , eicosanoids , leukotrienes , and cytokines ) involved in inflammation . Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability .

Die häufigsten unerwünschten Wirkungen sind Candida-albicans -Infektionen der Mund- und Rachenschleimhaut ( Mundsoor ). Häufig werden auch Infekte der oberen Luftwege, Heiserkeit, Lungenentzündung bei COPD -Patienten, Kopfschmerzen , Müdigkeit, Verletzlichkeit der Haut und Blutergüsse beobachtet. Um eine unerwünschte Wirkung auf die Mund- und Rachenschleimhaut zu vermeiden, sollte nach der Inhalation der Mund mit Wasser gespült oder etwas gegessen werden. Zu den sehr seltenen unerwünschte Wirkungen gehören Quincke-Ödeme , Allergien , Cushing-Syndrom , Hemmung der Nebennierenrinden-Funktion , Wachstumsverzögerung bei Kindern und Jugendlichen, verminderte Knochendichte , Glaukom , Hyperglykämie, Angstgefühl, Schlafstörungen, Verhaltensveränderungen und paradoxer Bronchospasmus .

Fluticasone propionate generic

fluticasone propionate generic

Media:

fluticasone propionate genericfluticasone propionate genericfluticasone propionate genericfluticasone propionate genericfluticasone propionate generic

http://buy-steroids.org