So glad I found your site after reading all the other alarming information. I was diagnosed a year ago with LS, but everyone has talked of Gynaecologist referals so how come I ended up in Dermotology? What worries me are the lumps & bumps which are referred to and which I have plus blisters. Help is this normal? I am using an emulent based cream for washing & barrier protection & a stronger steriod cream (as the first cream didn’t work, but having said that, was I not using enough, as they say sparingly!) How do you know if you are reacting to the creams etc with this problem? How demoralised I feel as a woman who looked forward to & shortly enjoyed the freedom of sex after her hysterectomy to now not being able to have sex. (Sorry feeling low). Its also funny that after the ‘op’ I started swimming again & it is said that clorine can affect you, it was a few months after when problems started together with a reaction to 2 medications really kick started it. I also have read that you can be alergic to ‘sperm fluid’ is this then also another starting point after the ‘op’ since previous protection used?
In a review article on “Drug Metabolism and Variability among Patients in Drug Response” published in the New England Journal of Medicine , Wilkinson (2005) stated that “there have not yet been prospective clinical trials showing that knowledge of a patient’s genotypic profile before prescribing drugs either increases drug efficacy, prevents or reduces adverse drug reactions, or lower the overall costs of therapy and associate sequelae …. For now, however, the individual patient is probably best served by an alert physician aware of the possibility that a genetic polymorphism in drug metabolism may be a potential factor in unexpected drug response”.