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Oral exemestane 25 mg/day for 2–3 years of adjuvant therapy was generally more effective than 5 years of continuous adjuvant tamoxifen in the treatment of postmenopausal women with early-stage estrogen receptor-positive/unknown receptor status breast in a large well-designed [ citation needed ] trial. Preliminary data from the open-label TEAM trial comparing exemestane with tamoxifen indicated in 2009 that exemestane 25 mg/day is also effective in the primary adjuvant treatment of early-stage breast cancer in postmenopausal women. [17]

Combined preparations . A number of trials have been carried out with implants containing two hormones. The combination of an oestrogen with an anabolic steroid, or with progesterone, has met with the greatest responses. Synovex-S has consistently increased gain as well as FCE, with responses averaging about 20% and 17% respectively (20, 21, 22, 34, 35, 36, 37, 42, 43, 44, 45, 46, 47, 48). Hexoestrol + TBA (usually 30 or 45 mg hexoestrol + 300 mg TBA) has resulted in marked increases in gain (24, 25, 26, 29, 49, 50, 51, 52, 53), of the order of 30% and in FCE (25, 49, 50, 51, 53) of the order of 20%. Oestradiol-17β + TBA (20/140 mg) has given similar results (27, 28, 37, 54, 55), as has Zeranol + TBA (36/300 mg), also recently tested (27, 37, 38, 39, 40, 41, 56).

Trenbolone daily dose

trenbolone daily dose

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